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          Solutions of Recombination Protein Process Filtration

          Recombination Protein Process-Filtration-cbt.jpg

          Recombinant human insulin is the world's first recombinant protein drug marketed for the treatment of type 1 and type 2 diabetes and has been used for more than 30 years. Development, insulin has now evolved from the first generation of animal-derived insulins to the fourth generation of long-acting insulin analogs. 


          Recombinant human insulin is the world's first recombinant protein drug marketed for the treatment of type 1 and type 2 diabetes and has been used for more than 30 years. Development, insulin has now evolved from the first generation of animal-derived insulins to the fourth generation of long-acting insulin analogs. 


          Recombinant protein drugs including:

          1. Peptide hormones - recombinant human insulin, insulin analogs, recombinant human growth hormone and recombinant human follicle stimulating hormone, etc.

          2. Cytokines -recombinant human follicle maturation hormone, recombinant human interferon  α、β、γ、 recombinant human granulocyte macrophage-stimulating factor, recombinant human erythropoietin, recombinant human interleukin 2,11, recombinant human epidermal growth factor. Recombinant human fibroblast growth factor, etc.

          3. Recombinant enzymes - recombinant human urokinase progenitors, recombinant human α glucosidase preparations, etc., and others such as recombinant human bone formation Protein 2 and recombinant hirudin in various segments. 


          The development of recombinant protein drugs is now in a stable phase and new technologies are important to extend the half-life of the drug in the body and change the form of delivery. Research into long-acting drugs is ongoing.



          Solutions of Recombination Protein Process Filtration-cbt.jpg    

          ① Vent and Gas Filtration       

          Safesure AFM -Hydrophobic PTFE

          Aegivast ACE -Hydrophobic PTFE
          Corevital APB -Hydrophobic PVDF



          Buffer Filtration

          Safetect?PME-PES
          Purcise?PLE-Double Layers PES
          Purcise?PAF-PES

          Purcise?SLE-Double Layers PES

          Purcise?SAF-Double Layers PES

          Corevital?SMD-PVDF



          ③ Clarification Filtration

          Roheap CSD

          Greclary?CHV-Glass Fiber

          Excesal?CHC-PP

          Excesal?CHE-PP
          Excesal?CHT-PP



          ④ Column / TFF Protection

          Purcise PLE -Double Layer PES
          Purcise PAF -PES
          Safetect PME -PES
          Corevital SAF -Double Layer PES

          Purcise SLE -Double Layer PES

          Purcise SPS -PES

          Corevital SMD -PVDF



          ⑤ Concentration and Purification

          Consieve?UET-PES



          ⑥ Sterile Filtration

          Purcise?SLE-Double Layer PES

          Purcise SPS -PES



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